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体育活动调节久坐行为诱发抑郁症的生物学机制研究
徐帅,季泰,余锋,谌晓安
(吉首大学 体育科学学院,湖南 吉首 416000 ;淮阴师范学院 体育学院,江苏 淮安 223300;上海交通大学 体育系,上海 200240)
摘要:
久坐行为被认为是影响机体身心健康的先兆因素,久坐行为可引起抑郁症的发生发展。在久坐行为与抑郁症的相关性分析中,不同人群均存在久坐行为诱发抑郁的现象,且成人的久坐时长增加,罹患抑郁症的风险更高。在生物学机制中,久坐行为可诱导大脑功能障碍、神经营养因子紊乱以及肠道菌群紊乱,诱发抑郁症。体育活动的增加导致久坐行为的减少,将会对抑郁起到明显的改善作用,其机制为:体育活动可缓解精神压力,提高神经功能和肠道菌群功能,最终缓解抑郁症的发展。
关键词:  久坐行为  抑郁症  行为特征  神经功能  肠道菌群
DOI:
投稿时间:2023-03-06
基金项目:湖南省哲学社会科学基金课题(19YBA283);江苏省教育科学十三五规划重点课题(T-a/2020/04);上海市哲学社会科学规划青年课题(2019ETY002);江苏省社会科学基金一般项目(22TYB005)
Study on the Biological Mechanism of Physical Activity Modulating Sedentary Behavior Induced Depression
XU Shuai,JI Tai,YU Feng,CHEN Xiaoan
(School of Physical Education and Sports Science,Jishou University,Jishou 416000 ,China ;School of Physical Education,Huaiyin Normal University,Huai’an 223300 ,China;SJTU Sport,Shanghai Jiao Tong University,Shanghai 200240 ,China)
Abstract:
Sedentary behavior is considered to be a precursor factor affecting the physical and mental health of the body. Sedentary behavior can cause the occurrence and development of depression. In the correlation analysis between sedentary behavior and depression, the phenomenon of depression induced by sedentary behavior exists in different populations, and the risk of depression is higher in adults with increased sedentary time. In the biological mechanism, sedentary behavior can induce brain dysfunction, neurotrophic factor disorder and intestinal flora disorder, and induce depression. The increase in physical activity leads to a decrease in sedentary behavior, which will significantly improve depression. The mechanism is that physical activity can relieve mental stress, improve neurological function and intestinal flora function, and ultimately alleviate the development of depression.
Key words:  sedentary behavior  depression  behavioral characteristics  nervous function  intestinal flora

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