摘要: |
目的:基于客观测量的体力活动,探讨体力活动与老年人认知能力之间的剂量效应关系。方法:采用 ActiGraphGT3X+测量老年人的体力活动,通过 《简易精神状态评价量表》中国版评定老年人的认知能力,利用线性回归模型分析体力活动与老年人认知能力之间的剂量效应关系。结果:在 600名受试者中,体力活动和认知能力测试数据均完整有效的共512名 (男245名,女267名),线性回归分析结果显示,校正了年龄、BMI、最高学历、月平均收入因素后,MVPA 对老年人认知能力产生显著影响 (P<0.01),且对女性的改善效果好于男性 (标准化系数0.693>0.548);LPA 仅对女性老年人认知能力影响显著 (P<0.01)。将 MVPA 按照四分位数间距分成4组时发现,MVPA 与老年人认知能力之间存在倒 “U”型剂量效应关系,在 4 个模型中,Q2 组 (21.13 min/day≤ MVPA<34.49min/day)MVPA 对认知能力影响的β系数大于其他三组,并未发现 LPA 与女性老年人之间呈现规律的剂量效应关系。结论:体力活动能显著改善老年人的认知能力,MVPA 的改善效果好于 LPA;体力活动对老年人认知能力的影响存在性别差异,MVPA 每提高10min/day,男、 女认知能力得分分别提高约0.48分、0.71分,LPA 每提高10min/day,女性认知能力得分提高约 0.07分;MVPA 与老年人认知能力之间存在倒" U" 型剂量效应关系,21.13-34.49 min/day 的 MVPA 对老年人认知能力的改善效果最佳。 |
关键词: 老年人 体力活动 认知能力 剂量效应关系 MVPA LPA |
DOI: |
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基金项目:江苏省社会科学基金项目 “江苏体医深度融合协同发展路径研究”(19TYB008) |
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Study on the Dose-effect Relationship between Physical Activity and Cognitive Function in the Elderly with Mild Cognitive Impairment |
WEI Xianjun,ZHANG Yu |
(Ministry of Sports,Nanjing University of Finance and Economics,Nanjing 210046 ,China;Faculty of Physical Education, Qilu Normal University,Jinan 250200 ,China) |
Abstract: |
Objective: This paper explores the dose-response relationship between physical activity and cognitive ability in the elderly based on objective measured physical activity. Methods:Actigraph GT3X+ is used to measure the physical activity of the elderly, and the cognitive ability of the elderly is evaluated by the Chinese version of the Simple Mental State Assessment Scale. The dose-response relationship between physical activity and cognitive ability of the elderly is analyzed by using a linear regression model.Results:Among 600 subjects, there are 512 (245 males and 267 females) complete and valid physical activity and cognitive ability test data. Theresults of linear regression analysis show that after adjusting for age,body mass index(BMI), highest education level and monthly average income, Moderate to Vigorous Physical Activity (MVPA) has a significant effect on the cognitive ability of the elderly (P<0.01), and the improvement effect of MVPA is better in women than in men (standardized coefficient 0.693>0.548). Light-intensity PA (LPA) only has significant effect on the cognitive ability of female elderly (P<0.01). When MVPA is divided into four groups according to the quantile interval, it is found that there is an inverted “U” type dose-effect relationship between MVPA and cognitive ability of the elderly. Among the four models, the β coefficient of MVPA on cognitive ability in Q2 group (21.13 min/day≤MVPA<34.49 min/day) is higher than that in the other three groups. No regular dose-response relationship is found between LPA and the elderly women. Conclusion: Physical activity can significantly improve the cognitive ability of the elderly, and the improvement effect of MVPA is better than LPA. The effect of physical activity on the cognitive ability of the elderly is different between men and women. The cognitive ability scores of men and women are increased by 0.48 and 0.71 points, respectively, when MVPA was increased by 10min/day, and the cognitive ability scores of women are increased by 0.07 points when LPA is increased by 10min/day. There is an inverted “U” type dose-effect relationship between MVPA and the cognitive ability of the elderly, and the MVPA with21.13 min/day≤MVPA and 34.49 min/day has the best improvement effect on the cognitive ability of the elderly. |
Key words: elderly people physical activity cognitive ability dose-effect relationship MVPA LPA |